Karmanos Cancer Institute Grand Rounds
  Thursday, January 25, 2018
4:30 p.m.
Location: 2nd Floor Wertz Auditorium


"Regulation of the DNA Damage Response"

Tanya T. Paull, Ph.D.
Investigator, Howard Hughes Medical Institute
Professor, Department of Molecular Biosciences
University of Texas at Austin



CB7700 - Journal Club Winter 2018
Time: 12:00 p.m. 
Location: Karmanos Cancer Institute Wertz Classroom
Student Presenting: 
Aamod Dekhne
Faculty mentor:
Dr. Michael Joiner
Krause, DJ et al "Favorable Preliminary Outcomes for Men With Low- and Intermediate-risk ProstateCancer Treated With 19-Gy Single-fraction High-dose-rate Brachytherapy." Int J Radiat Oncol Biol Phys. 2017 Jan 1;97(1):98-106.


Congratulations Andrew S. Murray, PhD for successfully defending your dissertation.

"Identifying the role of the Type-II transmembrane serine protease TMPRSS13 in breast cancer"

 Mentor: Karin List, PhD


Congratulations Daniel Feldmann, Ph.D. on successfully defending your dissertation

"Preparation and Utility of Polymeric Nanoparticles for the Delivery of siRNA as Cancer Therapy"

Mentors: Olivia Merkel, PhD & Stephan Patrick, PhD


Congratulations Ethan Brock, Anthony Guastella and Asra Shaik - F31 Fellowships Recipients


Congratulations Thomas McFall for successfully defending your PhD dissertation

"Mechanisms of Hormonal Regulation of Invasiveness and Metastasis of Luminal Breast Cancer"

Mentor: Manohar Ratnam, PhD


Congratulations Layne Weatherford  for successfully defending your PhD dissertation

"Functions of ATR/Mec1 in Meiosis and the Cell Cycle"

Mentor: George Brush, PhD


Congratulations Larry Matherly, Ph.D. on the renewal of the Ruth L. Kirschenstein Research Training Grant (T32-CA009531), Wayne State University School of Medicine


Congratulations Stephanie J. Blocker for successfully defending your PhD dissertation

"PET Imaging of Early Therapeutic Response in Solid Tumors"

Mentor: Anthony F. Shields, M.D. Ph.D.


Congratulations Brittany M. Haynes for successfully defending your PhD dissertation

"Rad6-mediated Translesion Synthesis Promotes Fanconi Anemia and Homologous
Recombination in Repair of Platinum-induced DNA Damage"

Mentor: Malathy Shekhar, PhD

Congratulations Jonathan D. Diedrich for successfully defending your PhD dissertation
"The Effects of Bone Marrow Adipocytes on Metabolic Regulation in Metastatic Prostate Cancer"
Mentor: Izabela Podgorski, PhD

Congratulations Rayna C. Rosati for successfully defending your PhD dissertation
"New Mechanism Based Approaches for Treating Prostate Cancer"

Mentor: Manohar Ratnam, PhD


Congratulations Poster Prize Winners

Karmanos Cancer Institute 2017 Annual Molecular Therapeutics Research Symposium

FIRST PLACE: Joshua R Heyza
p52 modulates sensitivity to cisplatin and PARP inhibitors in ERCC1 null lung cancer cell lines

SECOND Place: Rayna Rosati
Small Molecule drugs to selectively disrupt ELK1 dependent growth signaling by AR in prostate cancer

THIRD PLACE: Ethan J Brock
Sprouty4 regulates ERK MAPK signaling and the transition to invasive breast ductal carcinoma


Inaugural Leonard N. Simons Award for Exemplary Research and Scholarly Achievement

Congratulations - Jonathan Diedrich


Congratulations to the following Cancer Biology Graduate Program Students for their outstanding achievement during the 7thAnnual Cancer Biology Research

Symposium held on Friday, March 31, 2017.

Oral Presentation Awards
1st Prize - Joshua Heyza

2nd Prize - Brooke McKnight

Poster Presentation Awards
1st Prize - Rayna Rosati
2nd Prize - Thomas McFall
3rd Prize - Brittany Haynes & C James Block


Congratulations Steven K. Jones for successfully defending your PhD dissertation.


"Folate Receptor Alpha Targeted Delivery and Characterization of Polyethyleneimine-graft-Polycaprolactone-block-Poly(ethylene glycol) Containing siRNA Micelleplexes"

Mentor: Olivia Merkel, PhD


Congratulations Andreana N. Holowatyj for successfully defending your Ph.D. dissertation. 

 "Clinicopathology and Molecular Determinants Underlying Benign Breast and  Breast Cancer Lesions"

Mentor: Michele L. Cote, PhD, MPH


Congratulations Jonathan Diedrich - Awarded a National Institute of Health F31 Fellowship


CB7890 Seminar in Cancer Biology - Every Thursday - 2nd floor Wertz Auditorium

Academic Year 2016 - 2017 CB7890 Seminar Presentation Schedule
Pointers Evaluation Form


CB7700 - Journal Club Winter 2017
Time: 12:00 p.m. Monday, March 27, 2017
Location: Karmanos Cancer Institute Wertz Classroom
Student Presenting: Garbriel Mpilla (1st Year student)

Faculty sponsor:

Paper: Day, KC et al.  "HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone." Cancer Res, 2017 Jan 1;77(1):74-85




BEST [Broadening Experiences in Scientific Training] is an NIH-funded initiative at Wayne State to assist new and current doctoral trainees in exploring all career options, not just those based in traditional research settings such as a university, but in fields like business, government, law, communication, and undergraduate education.

Please consider attending the BEST Program's Phase I panel discussions, to be held each afternoon during the subsequent week of Sept. 21-25 in Margherio, with individual sessions devoted to career explorations in the fields listed above (see the attached flyer).  Each session, hosted by a WSU faculty facilitator, comprises a panel of industry partners, domain specialists, and alumni who will lead an informed discussion about successful careers in these domains.  A Q&A will conclude each panel.

Please do not hesitate to let me know if you have questions or would like additional information.  You may also contact the BEST Program Coordinator, Dr. Heidi Kenaga, at>.

Congratulations! Andreana Holowatyj for being selected as Michigan's only representative during the inaugural AACR Capitol Hill Day to advocate for cancer research funding.

2016 Translational Research Cancer Centers Consortium For Emerging Therapies
Steven Jones - First Place Oral Presentation

Wayne State University Graduate Student Research Day 2015
Jonathan Diedrich - Poster Prize First Place
"Bone Marrow Adipocytes Alter the Metabolic Phenotype of Metastatic Prosate Cancer Cells"


14th International Society for Tryptophan Research (ISTRY) Conference
Anthony Guastella - Poster Presentation - First Place

"Tryptophan metabolizing enzymes in patient-derived xenograft models of glioblastoma using molecular imaging and immunohistochemical studies"


2015 American Society for Biochemistry and Molecular Biology, Special Symposium on Membrane-Anchored Serine Proteases
Andrew Murray - Poster Presentation - Third Place 
"Molecular characterization of the Type II Transmembrane Serine Protease TMPRSS13"

24th Annual Short Course on Experimental Models of Human Cancer - Bar Harbor, ME
Jackson Labs Scholarship - Jonathan Diedrich

42nd Annual Pharmacology Research Colloquium - U of T, UM, MSU, WSU
Jonathan Diedrich - Poster Presentation - Second Place


Ivory Dean, Ph.D. - Congratulations for representing the School of Medicine, Cancer Biology Graduate Program as the Student Commencement Speaker for the December 2014 Commencement Ceremony, Saturday, December 6, 2014.


2014 Summer Undergraduate Research Program

Undergraduate fellows represent the future of cancer research

Undergraduates complete 10-week research fellowship with Cancer Biology Graduate Program

Wayne State Students earn top spots in Karmanos research symposium poster contest 

Cancer Biology graduate students shine in annual reseach symposium 

Detroit Public Television - Discover the 'D' Series - Airing on Mondays @ 5:30 pm. Episode 1047. (Click the link for the page).
Featuring Wayne State University and highlighting the School of Medicine campus and the Cancer Biology
Graduate Program. See Dr. Matherly's lab and students Michael R. Wilson and Brittany Haynes in the documentary.