School of Medicine

Wayne State University School of Medicine

Ahmad Heydari







Ahmad Heydari, Ph.D
3025 Science Hall
Department of Nutrition and Food Science
Detroit, MI 48202

Research Interests:
Understanding the Secrets of Aging and Cancer through Nutrition Intervention

Research Description:
The Heydari laboratory focuses on understanding the effect of nutrition intervention (i.e., caloric restriction, folate deficiency) on the molecular mechanisms of aging and cancer. We hope to accomplish this by investigating DNA damage and DNA repair (specifically, base excision repair) in mammalian systems (i.e., laboratory rodents) using recombinant DNA technology. We are constantly updating our website ( in order to provide you with up-to-date information regarding our research and relevant information on nutrition, aging, and cancer.

Selected Publications:

Barnes VL, Bhat A, Unnikrishnan A, Heydari AR, Arking R, Pile LA. SIN3 is critical for stress resistance and modulates adult lifespan. Aging (Albany NY). 2014;6:645-60

Soh JW, Marowsky N, Nichols TJ, Rahman AM, Miah T, Sarao P, Khasawneh R, Unnikrishnan A, Heydari AR, Silver RB, Arking R. Curcumin is an early-acting stage-specific inducer of extended functional longevity in Drosophila. Exp Gerontol. 2013;48:229-39.

Raffoul JJ, Heydari AR, Hillman GG. DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents. J Oncol. 2012;2012:370481.

Unnikrishnan A, Prychitko TM, Patel HV, Chowdhury ME, Pilling AB, Ventrella-Lucente LF, Papakonstantinou EV, Cabelof DC, Heydari AR. Folate deficiency regulates expression of DNA polymerase β in response to oxidative stress. Free Radic Biol Med. 2011;50:270-80.

Education and Training
BS in Microbiology (1984): Southern Illinois University, Carbondale, Illinois
MS in Biological Sciences (1988): Illinois State University, Normal, Illinois
PhD in Biological Sciences (1990): Illinois State University, Normal, Illinois