School of Medicine

Wayne State University School of Medicine

Aaron Burr

 

Aaron Burr
Senior Student

Dissertation Mentor: Dr. Sokol V.Todi, PhD

Research Focus: The role(s) of ubiquitin ligases and conjugases in cellular biology and ubiquitindependent pathways (including quality control mechanisms like ERAD) in order to determine how their regulation (or “dysregulation”) impacts human disease such as malignancies.

Grants, Awards, Scholarships:
Principles of Clinical Pharmacology course completion - National Institutes of Health, 2010-2011
Poster presentation prize winner - Cancer Biology Research Symposium, WSUSOM, 2012
Poster presentation prize winner - Graduate Student Research Day, WSUSOM, 2012
NRSA T32-CA009531
Training Grant Fellowship  (2012-13, 2013-14)
Oral presentation prize winner - Pharmacology Research Colloquium, WSUSOM, 2013
American Society for Cell Biology Travel Award - 2013
Cancer Biology Research Symposium Poster Presentation Award - Fourth Place

Committee(s):
Member of the Student Rep Committee for the 2012-2013 School Year
Member of the CB Curriculum Committee for the 2012-2013 School Year

Publication(s):

Burr AA, Tsou W-L, Ristic G, Todi SV (2014), Using membrane-targeted GFP to monitor neurotoxic protein-dependent degeneration of Drosophila eyes. J. Neurosci. Res. 2014;92:1100-9

Blount JR, Tsou W-L, Ristic G, Burr AA, Ouyang M, Galante H, Scaglione KM, Todi SV. Ubiquitinbinding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad 23. Nat Commun. 2014;5:4638.

Baker S, Vidican CB, Cameron D, Greib H, Jarocki CC, Setaputri AW, Spicuzza C, Burr A, Waqas MA, Tolbert DA. An epifluorescent attachment improves whole plant digital photography of Arabidopsis thaliana expressing red-shifted green fluorescent protein. AoB PLANTS. 2012;13.

Tsou W-L, Burr AA, Ouyang M, Blount JR, Scaglione KM, Todi SV. Ubiquitination regulates the neuroprotective function of the deubiquitinase ataxin-3 in vivo. J. Biol. Chem. 2013;288:34460-9.

Education:
University of Detroit Mercy, B.S. Biology 

Hometown:
Southgate, Michigan