Anthony Guastella

Anthony Guastella
4th Year

Dissertation Mentor: Sandeep Mittal, M.D.

Grants, Awards & Scholarships:

2017 - 2018 F31 Ruth L. Kirschstein National Research Service Award for Individual Predoctoral Fellows
2016 - 2017 Ruth L. Kirschenstein Research Training Recipient (T32-CA009531), Wayne State University
AGEP Scholar's Award 2015
AGEP Scholar's Award 2016
TRCCC Travel Grant Award 2016
NIH/NIGMS Metabolomics Workshop Travel Fellowship Award 2016
14th International Society for Tryptophan Research (ISTRY) Conference - First Place Poster Presentation
2015/16 Initiative to Maximize Student Development (IMSD) Fellowship
2015 Cancer Biology Research Symposium Poster Presentation Award 1st Place
2014/15 Cancer Biology Director's Award, Wayne State University School of Medicine
2014/15 Dean's Diversity Fellowship
2014 Summer Undergraduate Research Fellowship

Publications:

Guastella AR, Michelhaugh SK, Klinger NV, Kupsky WJ, Polin LA, Muzik O, Juhasz C and Mittal S. Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging 2016;15.

Michelhaugh SK,* Muzik O,* Guastella AR,* Klinger NV, Polin LA, Cai H, Xin Y, Mangner TJ, Zhang S, Juhasz C and Mittal S. Assessment of tryptophan uptake and kinetics using 1-(2-[18F]fluoroethyl)-L-tryptophan and alpha-[11C]-methyl-L-tryptophan PET imaging in mice implanted with patient-derived brain tumor xenografts. J Nucl Med 2016. *Authors contributed equally

Targeting the Broadly Pathogenic Kynurenine Pathway Guastella AR, Michelhaugh SK, Mittal S. 2015th ed. Mittal S, editor. New York: Springer; 2015. Chapter 25, Experimental models to study the kynurenine pathway. 480p.

Targeting the Broadly Pathogenic Kynurenine Pathway Michelhaugh SK, Guastella AR, Mittal S. 2015th ed. Mittal S, editor. New York: Springer; 2015. Chapter 1, Overview of the kynurenine pathway. 480p.

Targeting the Broadly Pathogenic Kynurenine Pathway Michelhaugh SK, Varadarajan K, Guastella AR, Mittal S. 2015th ed. Mittal S, editor. New York: Springer; 2015. Chapter 23, Role of kynurenine pathway in neuro-oncology. 480p.

Bosnyak E, Kamson DO, Guastella AR, Varadarajan K, Robinette NL, Kupsky WJ, Muzik O, Michelhaugh SK, Mittal S, Juhasz C. Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. Neuro-oncology 2015;17-1284-92.

Michelhaugh SK, Guastella AR, Varadarajan K, Klinger NV, Parajuli P, Ahmad A, Sethi S, Aboukameel A, Kiousis S, Zitron IM, Ebrahim SA, Polin LA, Sarkar FH, Bollig-Fischer A, and Mittal S. Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1. J Transl Med 2015;13:227.

Education:
Oakland University, Rochester, MI. BS Biology minor: Physics

Hometown:
Rochester Hills, Michigan