School of Medicine

Wayne State University School of Medicine

Joshua Heyza

Joshua Heyza
3rd Year

Dissertation Mentor: Stephan Patrick, Ph.D.

Research Focus: 
Understanding the role of p53 in mediating sensitivity to platinum-based chemotherapy in NER-deficient tumors. Identifying mechanistic roles of ERCC1 splice variants in modulating cisplatin cytotoxicity. 


Grants, Awards & Scholarships:
2016 - 2017 Ruth L. Kirschenstein Research Training Recipient (T32-CA009531), Wayne State University
18th Annual Midwest DNA Repair Symposium, The Ohio State University - 1st Place Poster Presentation
 6th  Annual Cancer Biology Symposium, Wayne State University School of Medicine - 1st Place Poster Presentation
2014 Cancer Biology Director’s Award, Wayne State University School of Medicine



Arora, S., Heyza, J., Zhang, H., Kalman-Maltese, V., Tillison, K., Floyd, A., Chalfin, E., Bepler, G., & Patrick, S. (2016). Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells. Oncotarget, 5. 2016 Sep 16. .

K. Ji, J. Heyza, D. Cavallo-Medved, B.F. Sloane, Pathomimetic Cancer Avatars for Live-Cell Imaging of Protease Activity, Biochimie 2016;122:68-76.

BS with Honors, Biology, University of Michigan-Flint

Flint, MI