School of Medicine

Wayne State University School of Medicine

Andreana Holowatyj

Andreana Holowatyj
4th Year Student

Dissertation Mentor: Michele L. Cote, PhD

Research Focus:
Epigenetics and chromatin modifications in tumorigenesis; Molecular epidemiology and disparities in cancers

Grants, Awards, Scholarships:

European Society of Medical Oncology IMPAKT 2017 Breast Cancer Conference Grant
AACR Cancer Research Catalyst Blog 2017 Guest Writer 
2017 European Association for Cancer Research Certificate of Recognition
Wayne State University Warrior Day 2017 State Capitol Representative
2017 American Association of Cancer Research (AACR) Early-Career Hill Day Representative 

2017 Wayne State University School of Medicine Graduate Student Professional Travel Award
2016 Population Studies and Disparities Research Program Research Retreat Poster Presentation Award 2nd Place

Komen for the Cure Graduate Training in Disparities Research Program Fellowship 2016-2017
European Association of Cancer Research 24th Biennial Congress Meeting Bursary Award
Midwest Association of Graduate Schools (MAGS) 2016 Inaugural Three Minute Thesis (3MT) Regional Finalist
2016 WSU Graduate Research Symposium Third Place Poster Presentation Award
Susan G. Komen Foundation: The Jon Shevell Young Scientist Travel Scholarship
Cancer Disparities Research Network 2016 Travel Scholarship, National Cancer Institute's Center to Reduce Cancer Health Disparities: GMaP Region Four
Three Minute Thesis (3MT) 2016 Wayne State University Competition Nominee & Representative
European Association for Cancer Research Certificate of Recognition
European Society of Medical Oncology IMPAKT 2016 Breast Cancer Conference Travel Grant

American Association of Cancer Research Early-career Hill Day 2016 Representative 
ESO Molecular Diagnostics, Genomics and Epigenetics in Clinical Oncology 2015 Travel Grant
Komen for the Cure Graduate Training in Disparities Research Program Fellowship 2015-2016
2015 Cancer Biology Research Symposium Poster Presentation Award 3rd Place
WSU School of Medicine Pre-Doctoral Student Professional Travel Award
EACR-OECI Conference on Precision Medicine for Cancer 2015 Participation Grant
2014 Molecular Therapeutics Research Symposium Poster Presentation Award 3rd Place
NIH Metabolomics Workshop Travel Fellowship Award
WSU Graduate Student Professional Travel Award
2014 Cancer Biology Research Symposium Poster Presentation Award 3rd Place
Emory University STEM Research and Career Symposium 2014 Travel Award
2013 KCI Institute Wide Research Retreat Poster Session Winner 1st Place
AAAS/Science Program for Excellence in Science
Cancer Biology Summer Research Fellowship
Cancer Biology Director's Award

Committees:
Michigan Science Center STEMinista Role Model 2016-2017
American Association for Cancer Research (AACR) AMC-led Annual Meeting 5K Run/Walk Sub-Committee Chair 2017
American Association for Cancer Research (AACR) AMC-led AACR Rock 'n' Roll Philadelphia Half Marathon Sub-Committee Chair 2016-2017
American Association for Cancer Research (AACR) AMC-led Flavor of the City Sub-Committee Member 2016-2017
American Association for Cancer Research (AACR) AMC-led Fundraising Committee 2016-2017
European Association for Cancer Research (EACR) Ambassador 2015-2017
Cancer Biology Recruitment Committee Student Chair 2015
Cancer Biology Symposium Planning Committee 2015
Cancer Biology Recruitment Committee Student Chair 2014
Graduate Student Research Day (GSRD) Committee Chair 2014
Cancer Biology Symposium Planning Committee 2014

Publications:

Holowatyj AN, Ruterbusch JJ, Rozek LS, Cote ML, Stoffel EM. Racial/ethnic disparities in survival among patients with young-onset colorectal cancer. Journal of Clinical Oncology. 2016;34:2148-56

Holowatyj AN, Ruterbusch JJ, Ratnam M, Gorski DH, Cote ML. HER2 status and disparities in luminal breast cancers. Cancer Medicine. 2016;5:2109-16.

Ye Q*, Holowatyj A*, Wu J, Liu H, Zhang L, Suzuki T, Yang ZQ. Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer. Am J Cancer Res. 2015;5:1519-30. *Contributed equally to this work.

 Holowatyj A, Yang ZQ, Pile L. Histone lysine demethylases in Drosophila melanogaster. Fly. 2015;9:36-44.

 Liu H, Liu L, Holowatyj A, Jiang Y, Yang ZQ. Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer. Molecular Carcinogenesis. 2016;55:977-90.

Liu L, Kimball S, Liu H, Holowatyj A, Yang ZQ. Genetic alterations of histone lysine methyltransferases and their significance in breast cancer. Oncotarget. 2015;6:2466-83.

Ye Q, Holowatyj A, Labbe R, Liu H, Yang ZQ. The emerging functions and therapeutic application of the histone lysine demethylase lysine-specific demethylase 4 subfamily. Translational Medicine Journal, 2014;3:13-18. (Chinese)

Labbé RM, Holowatyj A, Yang ZQ. Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential. Am J Transl Res. 2013;6:1-15.

Sun LL, Holowatyj A, Xu XE, Wu JY, Wu ZY, Shen JH, Wang SH, Li EM, Yang ZQ, Xu LY. Histone demethylase GASC1, a potential prognostic and predictive marker in esophageal squamous cell carcinoma. Am J Cancer Res. 2013;3:509-17.

Holowatyj A, Yang ZQ. The Role of Histone Demethylase GASC1 in Cancer and its Therapeutic Potential. Current Cancer Therapy Reviews 2013;9:78-85.

Hou J, Wu J, Dombkowski A, Zhang K, Holowatyj A, Boerner JL, Yang ZQ. Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer. Am J Transl Res. 2012;4:247-5

Education:
Wayne State University School of Medicine: Graduate Certificate in Public Health Practice (GCPHP), 2016.
Benedictine University: Bachelor of Arts degree with Honors, Medical Humanities and Mathematics, 2013.
Dalian Medical University (China): Visiting Scholar, College of Stomatology, 2013.
Victoria University of Wellington (New Zealand): 2011-2012.
Universita Karlova (Czech Republic): 2011.

Hometown:
Chicago, Illinois