School of Medicine

Wayne State University School of Medicine

Rayna Rosati

Rayna Rosati
Senior Student

Dissertation Mentor: Manohar Ratnam, PhD

Research Focus: Studying the Elk1-AR interaction as a potential target for treating prostate cancer.

Grants, Awards, Scholarships:
2016-2017 Thomas C. Rumble University Graduate Fellowship
2016 Molecular Therapeutics Annual Research Symposium Poster Presentation Award, 2nd Place
2016  Cancer Biology Research Symposium Poster Presentation Award 3rd Place
2015-2016 NRSA T32 Training Grant Fellowship Reappointment
2015 Molecular Therapeutics Annual Research Symposium Poster Presentation Award, 3rd Place
2015 Cancer Biology Research Symposium Oral Presentation Award, 1st Place
2014-2015 NRSA T32 Training Grant Fellowship
2014 Cancer Biology Research Symposium Poster Presentation Award, 1st Place
2012-2016 AAAS/Science Program for Excellence in Science
2012 Cancer Biology Director's Award
2011 Knobloch Endowment Scholarship by the University at Buffalo’s Biology Department

Professional Development/ Committees:
2016 Komen Race for the Cure: Researchers at the Race
2016 Komen Race for the Cure Planning Committee
2016 Cancer Biology Student Recruitment Day Chair
2015-2016 American Association for Cancer Research Associate Member
2015 Komen Race for the Cure: Researchers at the Race
2015 Cancer Biology Symposium Planning Committee 
2014-2015 Cancer Biology Student Representative
2014-2015 American Association for Cancer Research Associate Member 
2014 Graduate Student Research Day Planning Committee 
2014 Cancer Biology Symposium Planning Committee 
2013-2014 American Association for Cancer Research Associate Member
2013 Cancer Biology Symposium Planning Committee

Publication(s):

Rosati, R., Patki, M., Chari, V., Dakshnamurthy, S., McFall, T., Saxton, J., Kidder, B.L., Shaw, P.E. and Ratnam, M. The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth. The Journal of biological chemistry. 2016.

Movassaghian S, Xie Y, Hildebrandt C, Rosati R, Li Y, Kim NH, Conti DS, da Rocha SR, Yang ZQ and Merkel OM. Post-Transcriptional Regulation of the GASC1 Oncogene with Active Tumor-Targeted siRNA-Nanoparticles. Molecular pharmaceutics. 2016; 13(8):2605-2621.

Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M and Qin Z. Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells. Molecular pharmacology. 2016; 90(3):225-237. 

McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget 2015;6:33146-64.

Education:
University at Buffalo, BS in Biology graduated with honors

Hometown:
Hamburg, NY