Dissertation Mentor: Karin List, Ph.D.
Research Focus: Characterizing the post-translational modifications of the type II transmembrane serine protease TMPRSS13 in breast cancer.
Grants, Awards, Scholarships:
2020 - 2021 NIH Ruth L. Kirschenstein Research Training Recipient (T32-CA009531), Wayne State University
Poster Award, 46th Annual Pharmacology Research Colloquium, University of Toledo - 2019
Poster Award, ASBMB Symposium on Serine Proteases in Pericellular Proteolysis and Signaling, Potomac, MD - 2019
2019 - 2020 NIH Ruth L. Kirschenstein Research Training Recipient (T32-CA009531), Wayne State University
2017-2018 Cancer Biology Director's Award, Wayne State University School of Medicine
Murray AS, Hyland TE, Sala-Hamrick KE, Mackinder JR, Martin CE, Tanabe LM, Varela FA, List K. The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy. Oncogene 2020;39:6421-36.
Varela FA, Foust VL, Hyland TE, Sala-Hamrick KE, Mackinder JR, Martin CE, Murray AS, Todi SV, List K. TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer. Scientific Reports 2020;10:13896.
Martin CE, List K. Cell surface-anchored serine proteases in cancer progression and metastasis. Cancer Metastasis Rev. 2019;38:357-87.
Herroon MK, Diedrich JD, Rajagurubandara E, Martin C, Maddipati K, Kim S, Heath EI, Granneman J, and Podgorski I. Prostate tumor cell-derived IL-1β induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms. Molecular Cancer Research 2019;17:2508-21.
Gajan A, Martin CE, Kim S, Joshi M, Michelhaugh SK, Slomo I, Mittal S, Firestine S, and Shekhar MP. Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization. Cells 2019;8:1375.
Education: University of Michigan-Ann Arbor - B.S. Microbiology (2016)
Hometown: Berkley, MI